A major international study of the genetics of breast cancer has identified more than 350 DNA ‘errors’ that increase an individual’s risk of developing the disease. The scientists involved say these errors may influence as many as 190 genes.
Innovation should support societal responsibility for health, comment Carol Brayne and others in BMJ
The popular emphasis on technology being harnessed by individuals fails to consider how it can be used to improve social determinants of health, say Richard Milne, Edo Richard, Eric B Larson, and Carol Brayne
Study highlights potential for ‘liquid health check’ to predict disease risk
Proteins in our blood could in future help provide a comprehensive ‘liquid health check’, assessing our health and predicting the likelihood that we will we will develop a range of diseases, according to research published today in Nature Medicine.
Opinion: Depression – men far more at risk than women in deprived areas
Depression is a major cause of disability around the world, and if left untreated, can lead to substance abuse, anxiety and suicide. Major depressive disorder is a particular form of the condition which affects many people, potentially causing loss of pleasure in activities that once used to bring joy. It can also lead to feelings […]
Switching to ‘green’ inhalers could reduce carbon emissions and cut costs, study suggests
Metered-dose inhalers contain liquefied, compressed gases that act as a propellant to atomise the drug being delivered and to pump it out to the user. Originally chlorofluorocarbons (CFCs), were used as the propellant but these potent greenhouse gases and ozone-depleting substances are now banned. Instead they have been replaced by hydrofluoroalkane (HFA) propellants. While HFAs […]
Type 2 diabetes remission possible with ‘achievable’ weight loss
People who achieve weight loss of 10% or more in the first five years following diagnosis with type 2 diabetes have the greatest chance of seeing their disease go into remission, according to a study led by the University of Cambridge. The findings suggest that it is possible to recover from the disease without intensive […]
Snack tax may be more effective than a sugary drink tax to tackle obesity, according to a new modelling study
September 5, 2019 Taxing high sugar snacks such as biscuits, cakes, and sweets might be more effective at reducing obesity levels than increasing the price of sugar sweetened drinks, suggests a study from Professor Theresa Marteau and colleagues, published in The BMJ. The effect seen in this study was double that seen for a similar […]
New PHG Foundation Senior Fellows Announced
PHG Foundation is delighted to announce the appointment of six outstanding professionals as Senior Fellows. This new PHG Foundation accolade is reserved for select individuals from across the world who have made significant professional contributions to fields closely related to PHG Foundation’s own policy work around genomics and biomedicine, and who have been great supporters […]
A “shared information” approach identifies novel associations in immune-mediated diseases
Genetic associations for related diseases, such as those that are immune-mediated, are often identified in the same genomic regions and are likely to share some genetic variants that play a role in disease susceptibility. Associated variants usually do not affect disease risk, rather they are highly correlated with the causal variant(s) for disease risk, and […]
Type 2 diabetes: small reduction in alcohol, big reduction in heart disease risk
Jean Strelitz writes about new research which indicates that reducing alcohol use by as little as two units per week may have long-term health benefits for people with diabetes. This post was originally published in The Conversation. People with type 2 diabetes are at a higher risk of getting cardiovascular diseases, including heart attack and stroke. Lifestyle factors, such […]
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